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Patents

Diode Pumped Alkali Vapor Fiber Laser
Stephen A. Payne, Raymond J. Beach, Jay W. Dawson, William F. Krupke
U.S. Patent 7,286,575 B2
October 23, 2007
This apparatus produces or amplifies near-diffraction-limited laser light in diode-pumped alkali vapor photonic-band-gap fiber lasers or amplifiers. Laser light is generated and propagated in an alkali gas instead of a solid to circumvent the nonlinear and damage limitations of conventional solid-core fibers. Alkali vapor is introduced into the center hole of a photonic-band-gap fiber, which can be configured as an amplifier or pumped with light and operated as an oscillator with a seed beam.

Computational Model, Method, and System for Kinetically-Tailoring Multi-Drug Chemotherapy for Individuals
Shea Nicole Gardner
U.S. Patent 7,286,970 B2
October 23, 2007
This system tailors treatment regimens for patients whose diseased cells resist treatment. A mathematical model provides rates of population change for proliferating and quiescent diseased cells. The model uses cell kinetics and resistance evolution as well as pharmacokinetic and pharmacodynamic models. Cell kinetic parameters for a patient are applied to the model to determine the treatment options and the quantitative efficacy value for each. A treatment regimen can then be selected based on the efficacy value.

Diagnostic System for Profiling Micro-Beams
John W. Elmer, Todd A. Palmer, Alan T. Teruya, Chris C. Walton
U.S. Patent 7,288,772 B2
October 30, 2007
This apparatus for characterizing a microbeam is composed of a micro-modified Faraday cup assembly with four layers of material. The first layer—an electrical conducting material with at least one radial slit extending through the layer—is connected to an electrical ground. The second layer, which connects to the first layer, is an insulating material with at least one radial slit corresponding to the slit (or slits) in the first layer. The third layer, a conducting material connected to the second layer, has at least one radial slit corresponding to the slit in the second layer. The fourth layer, an electrical conducting material with no slits, connects to the third layer and to an electrical measuring device. This micro-modified Faraday cup assembly is positioned to be swept by the microbeam.

Microfluidic Sieve Using Intertwined, Free-Standing Carbon Nanotube Mesh as Active Medium
Olgica Bakajin, Aleksandr Noy
U.S. Patent 7,290,667 B1
November 6, 2007
This microfluidic sieve has a substrate with a microfluidic channel and mesh made from intertwined freestanding carbon nanotubes for separating, concentrating, or filtering molecules. The microfluidic sieve can be fabricated by growing the intertwined freestanding carbon nanotubes within the microfluidic channel of a substrate.

Shape Memory Polymer Actuator and Catheter
Duncan J. Maitland, Abraham P. Lee, Daniel L. Schumann, Dennis L. Matthews, Derek E. Decker, Charles A. Jungreis
U.S. Patent 7,291,154 B2
November 6, 2007
This actuator system acts on a material in a vessel. The system includes a shape-memory polymer connected to an optical fiber. The polymer adapts from one shape for moving through the vessel to a second shape for acting on the vessel material.

Robotic CCD Microscope for Enhanced Crystal Recognition
Brent W. Segelke, Dominique Toppani
U.S. Patent 7,292,263 B2
November 6, 2007
A robotic charge-coupled device (CCD) microscope designed to automate crystal recognition provides more accurate results than other recognition methods. The system reduces the number of false negatives and false positives and can detect smaller crystals than other recognition methods.

Inspection Tester for Explosives
Jeffrey S. Haas, Randall L. Simpson, Joe H. Satcher
U.S. Patent 7,294,306 B2
November 13, 2007
An inspection tester designed for use by nontechnical personnel serves as a primary screening tool to determine whether a surface contains explosives. The tester body has a sample pad connected to a heater. Two holders and dispensers attached to the tester deliver explosives-detecting reagents to the sample pad.


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