Laser tracks therapeutics, nutrients, toxins

May 15, 2017- 
Lawrence Livermore National Laboratory (LLNL) researchers have developed a laser-based tabletop device to measure carbon-14 (radiocarbon). In biological systems, carbon-14 (14C ) can be used as a biochemical tracer to track micro-doses of nutrients, toxins and therapeutics in humans and animals. For example, the 14C can be tacked on to a vitamin. When a human ingests the vitamin...

New measurements of oceanic organic matter help scientists in understanding of climate

Nov. 16, 2016- 
Researchers have found that new measurements of the size, age and composition of organic matter in the Pacific Ocean affects short-term and long-term climate impacts. The findings could have implications for climate in terms of how long organic matter is stored in the ocean before being converted into CO2 and re-entering the atmosphere. Marine organic matter is one of Earth’s largest...

Lab, UC Davis partner to personalize cancer medications

Oct. 16, 2014- 
Buoyed by several dramatic advances, Lawrence Livermore National Laboratory scientists think they can tackle biological science in a way that couldn't be done before.Over the past two years, Lab researchers have expedited accelerator mass spectrometer sample preparation and analysis time from days to minutes and moved a complex scientific process requiring accelerator physicists into routine...

Biological sample prep time cut dramatically -- from days to minutes

Oct. 15, 2014- 
When Lawrence Livermore National Laboratory researchers invented the field of biological accelerator mass spectrometry (AMS) in the late 1980s, the process of preparing the samples was time-consuming and cumbersome. Physicists and biomedical researchers used torches, vacuum lines, special chemistries and high degrees of skill to convert biological samples into graphite targets that could...

Lawrence Livermore celebrates 25 years of carbon dating

July 23, 2013- 
From developing the first accelerator mass spectrometer for use in the biology field to tracking radionuclides from the Dai-ichi Nuclear Power Plant disaster, the Laboratory's Center for Accelerator Mass Spectrometry (CAMS) has spent 25 years in the spotlight of not only dating ancient artifacts but solving global challenges.CAMS is celebrating its 25th anniversary this Thursday (July 25)...

Carbon dating impacts non-proliferation, drug research and climate change

July 23, 2013- 
Research conducted at the Center for Accelerator Mass Spectrometry (CAMS) spans the universe, the depths of time and everything in between. Although not all elements and isotopes are able to be utilized by AMS, CAMS' researchers make the most of what nuclear physics has given them.Here is a sampling of some of the many ways CAMS is utilized, along with the important discoveries scientists...

CAMS used to determine biological effects of silica nanoparticles

Jan. 4, 2013- 
In a study published in a recent edition of Nano Letters , the Laboratory's Mike Malfatti, Heather Palko, Ed Kuhn and Ken Turteltaub report on accelerator mass spectrometry measurements used to investigate the relationship between administered dose, pharmacokinetics (PK), and long-term biodistribution of carbon 14-labeled silica nanopartocles in vivo .The increasing use of nanoparticles (NPs)...

Cold cases heat up through Lawrence Livermore approach to identifying remains

Oct. 10, 2012- 
LIVERMORE, Calif. -- In an effort to identify the thousands of John/Jane Doe cold cases in the United States, a Lawrence Livermore National Laboratory researcher and a team of international collaborators have found a multidisciplinary approach to identifying the remains of missing persons. Using "bomb pulse" radiocarbon analysis developed at Lawrence Livermore, combined with recently...

Insulin-creating cell research may lead to better diabetes treatment

Oct. 28, 2010- 
Beta cells, which make insulin in the human body, do not replicate after the age of 30, indicating that clinicians may be closer to better treating diabetes. Type 1 diabetes is caused by a loss of beta cells by auto-immunity while type 2 is due to a relative insufficiency of beta cells. Whether beta cells replicate after birth has remained an open issue, and is critically important...