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Synthetic Biology/Microbial Genetics/Biochemistry - Postdoctoral Researcher

Entry Level | Full-time
Physical Life Sciences | livermore, CA | 01/16/2024

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Company Description

Join us and make YOUR mark on the World!

Are you interested in joining some of the brightest talent in the world to strengthen the United States’ security? Come join Lawrence Livermore National Laboratory (LLNL) where our employees apply their expertise to create solutions for BIG ideas that make our world a better place.

We are committed to a diverse and equitable workforce with an inclusive culture that values and celebrates the diversity of our people, talents, ideas, experiences, and perspectives. This is essential to innovation and creativity for continued success of the Laboratory’s mission.

Pay Range

$108,840 Annually

Job Description

NOTE: This is a two-year Postdoctoral appointment with the possibility of extension to a maximum of three years.

Job scope description:

We are seeking a dedicated and hardworking Postdoctoral Researcher to conduct research in the fields of synthetic biology, microbial genetics, and biochemistry to study bacterial protein compartmentalization systems.  You will actively participate in research: (1) to probe the mechanistic basis for how these compartments are regulated, biosynthesized, and maintained, and (2) to engineer these systems in their native organisms to achieve new biosynthetic functions.  This position is in the Systems and Synthetic biology group in the Biosciences and Biotechnology Division.

In this role you will

  • Conduct fundamental research in synthetic biology, microbial genetics, and biochemistry to examine the bacterial encapsulin nanocompartment system from Rhodococcus species.
  • Employ cutting edge synthetic biology and protein engineering approaches to engineer encapsulin cages to support the biosynthesis of DOE relevant biomaterials.
  • Employ biochemical and genetic methods to probe mechanisms of encapsulin homeostasis.
  • Develop research plans, generate results, and publish peer-reviewed papers.
  • Regularly interact with a broad spectrum of computational and experimental scientists internally and externally to the Laboratory.
  • Publish research results in peer-reviewed scientific or technical journals and present results at external conferences, seminars, and/or technical meeting.
  • Work with other scientists to write proposals and expand our program into new areas aligned with your expertise and interests.
  • Perform other duties as assigned


  • Ph.D. in Bio/chemical engineering, Microbiology, Biochemistry, or a relevant field with a strong emphasis in microbial genetics and biochemistry.
  • Expertise in synthetic biology, genetics, protein engineering, and/or biochemistry.
  • Experience and knowledge microbial physiology, genetic manipulation, and/or characterization.
  • Experience in designing and constructing recombinant gene pathways in model bacteria (preferable non-E. coli).
  • Experience and knowledge in protein biochemistry, engineering, and/or characterization.
  • Ability to develop independent research projects as demonstrated through publication of peer-reviewed literature.
  • Proficient verbal and written communication and interpersonal skills to collaborate effectively in a multidisciplinary team environment and present and explain technical information.

Qualifications we desire

  • Experience with genetic manipulation, transposon mutagenesis, and/or omics in Rhodococcus species.
  • Experience with biomineralization of inorganic nanoparticles.
  • Experience with TEM, DLS, and/or XRD.
  • Experience with high throughput protein engineering techniques, including generation of variant libraries and selection strategies (e.g., via FACS).

Additional Information

All your information will be kept confidential according to EEO guidelines.

Position Information

This is a Postdoctoral appointment with the possibility of extension to a maximum of three years, open to those who have been awarded a PhD at time of hire date.

Why Lawrence Livermore National Laboratory?

Security Clearance

None required.  However, if your assignment is longer than 179 days cumulatively within a calendar year, you must go through the Personal Identity Verification process.  This process includes completing an online background investigation form and receiving approval of the background check.  (This process does not apply to foreign nationals.) 

Pre-Employment Drug Test

External applicant(s) selected for this position must pass a post-offer, pre-employment drug test. This includes testing for use of marijuana as Federal Law applies to us as a Federal Contractor.

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Equal Employment Opportunity

We are an equal opportunity employer that is committed to providing all with a work environment free of discrimination and harassment. All qualified applicants will receive consideration for employment without regard to race, color, religion, marital status, national origin, ancestry, sex, sexual orientation, gender identity, disability, medical condition, pregnancy, protected veteran status, age, citizenship, or any other characteristic protected by applicable laws.

We invite you to review the Equal Employment Opportunity posters which include EEO is the Law and Pay Transparency Nondiscrimination Provision.

Reasonable Accommodation

Our goal is to create an accessible and inclusive experience for all candidates applying and interviewing at the Laboratory.  If you need a reasonable accommodation during the application or the recruiting process, please use our online form to submit a request. 

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The California Consumer Privacy Act (CCPA) grants privacy rights to all California residents. The law also entitles job applicants, employees, and non-employee workers to be notified of what personal information LLNL collects and for what purpose. The Employee Privacy Notice can be accessed here.

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