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Biologist - Postdoctoral Researcher

Entry Level | Full-time
Physical Life Sciences | livermore, CA | 10/13/2021

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Company Description

Join us and make YOUR mark on the World!

Are you interested in joining some of the brightest talent in the world to strengthen the United States’ security? Come join Lawrence Livermore National Laboratory (LLNL) where our employees apply their expertise to create solutions for BIG ideas that make our world a better place.

We are committed to a diverse and equitable workforce with an inclusive culture that values and celebrates the diversity of our people, talents, ideas, experiences, and perspectives. This is essential to innovation and creativity for continued success of the Laboratory’s mission.

Job Description

NOTE: This is a two-year term appointment with the possibility of extension to a maximum of three years.

We have an opening for a Biology Postdoctoral Researcher to investigate blood brain barrier (BBB) dysfunction and viral pathogenesis in the brain. A successful candidate will join an interdisciplinary team working at the intersection of neuroscience, virology, and immunology, employing diverse cellular and molecular biology techniques. We value diverse perspectives and strongly encourage applications from historically underrepresented groups. This position is in Microbiology and Immunology Group of the Biosciences and Biotechnology Division.

In this role you will:

  • Design and conduct experiments in neuroimmunology, molecular biology, and cell biology in support of studies aimed at elucidating regulatory mechanisms of BBB integrity.
  • Employ mouse models of viral infection and BBB disruption
  • Develop and implement protocols for isolation of brain tissue for single cell RNA sequencing (scRNAseq) and spatial transcriptomic analysis.
  • Employ other methods of cellular and molecular characterization on mouse brain tissue such as histology, flow cytometry, qPCR, etc.
  • Pursue independent but complementary research interests and interact with a broad spectrum of scientists internally and externally to the Laboratory
  • Present formal and informal overviews of experimental progress at regular meetings.
  • Publish research results in peer-reviewed scientific or technical journals and present results at external conferences seminars and/or technical meetings.
  • Maintain and establish laboratory protocols, an accurate and detailed laboratory notebook including complete records of experiments.
  • Perform other duties as assigned.

Qualifications

  • PhD in Neuroscience, Virology, Immunology, Molecular Biology, Cell Biology, Microbiology, or related field.
  • Proficiency working with mice, including models of infectious disease, neurodegenerative disorders, and/or characterizing in vivo immune responses.
  • Proficiency isolating and processing mouse tissues for cellular and molecular analyses
  • Proficiency with one or more cellular/molecular characterization techniques, such as flow cytometry, histology, RNA sequencing, etc.
  • Ability to develop independent research projects as demonstrated through publication of peer-reviewed literature.
  • Proficient verbal and written communication and interpersonal skills to collaborate effectively in a multidisciplinary team environment and present and explain technical information.

Qualifications we desire:

  • Experience with scRNAseq and/or spatial transcriptomics and flow cytometry
  • Experience with histology (sample preparation, sectioning, staining for IHC, etc.)
  • Familiarity with sequencing data and with mouse models of behavioral studies.

Additional Information

Why Lawrence Livermore National Laboratory?

  • Included in 2020 Best Places to Work by Glassdoor!
  • Work for a premier innovative national Laboratory
  • Comprehensive Benefits Package
  • Flexible schedules (*depending on project needs)
  • Collaborative, creative, inclusive, and fun team environment

Learn more about our company, selection process, position types and security clearances by visiting our Career site

COVID-19 Vaccination Mandate

LLNL demonstrates its commitment to public safety by requiring that all new Laboratory employees be immunized against COVID-19 unless granted an accommodation under applicable state or federal law. This requirement will apply to all new hires including those who will be working on site, as well as those who will be teleworking.

Security Clearance

LLNL is a Department of Energy (DOE) and National Nuclear Security Administration (NNSA) Laboratory.  Most positions will require a DOE L or Q clearance (please reference Security Clearance requirement).  If you are selected, we will initiate a Federal background investigation to determine if you meet eligibility requirements for access to classified information or matter. In addition, all L or Q cleared employees are subject to random drug testing.  An L or Q clearance requires U.S. citizenship.  If you hold multiple citizenships (U.S. and another country), you may be required to renounce your non-U.S. citizenship before a DOE L or Q clearance will be processed/granted.  For additional information please see DOE Order 472.2.

Equal Employment Opportunity

LLNL is an affirmative action and equal opportunity employer that values and hires a diverse workforce. All qualified applicants will receive consideration for employment without regard to race, color, religion, marital status, national origin, ancestry, sex, sexual orientation, gender identity, disability, medical condition, pregnancy, protected veteran status, age, citizenship, or any other characteristic protected by applicable laws.

If you need assistance and/or a reasonable accommodation during the application or the recruiting process, please submit a request via our online form

California Privacy Notice

The California Consumer Privacy Act (CCPA) grants privacy rights to all California residents. The law also entitles job applicants, employees, and non-employee workers to be notified of what personal information LLNL collects and for what purpose. The Employee Privacy Notice can be accessed here.

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