Several activities are under way at LLNL to provide the medical community with additional protective measures so they can be better equipped to serve the public’s needs.
Emergency alternatives to hospital ventilators
- To address concerns about potential shortfalls in emergency room ventilators, we are actively researching and developing prototypes for how alternative equipment could be repurposed to meet excess demand. Download the COVID-19 Ventilator Brochure.
Methods for emergency cleaning and re-use of limited-supply personal protective equipment
- To address current shortfalls in new personal protective equipment, such as N95 masks and face shields, we are exploring rapid and effective decontamination procedures to enable temporary and emergency re-use of existing critical medical supplies.
- LLNL researchers have authored an accelerated publication: Quantitative form and fit of N95 filtering facepiece respirators are retained and coronavirus surrogate is inactivated after heat treatments
Rapid manufacturing capacity for critical consumable supplies to support diagnostics
- Sample collection swabs are among the scarce supplies that limit nationwide capabilities to test for the SARS-CoV-2 virus that causes COVID-19. LLNL is evaluating and validating multiple swab designs produced by different 3D printing approaches and materials.
- LLNL is participating in a working group of multiple other Department of Energy laboratories by using 3D printing to prototype and rapidly transition to manufacturing additional consumable components such as sample vials and replacement parts for critical equipment.
- Accelerated publication - High-Throughput Virtual Screening of Small Molecule Inhibitors for SARS-CoV-2 Protein Targets with Deep Fusion Models
- Publication - Quantitative Fit Evaluation of N95 Filtering Facepiece Respirators and Coronavirus Inactivation Following Heat Treatment
- Accelerated publication - Rapid in silico design of antibodies targeting SARS-CoV-2 using machine learning and supercomputing
- June 2, 2021 - Decontaminating N95 masks for reuse
- May 3, 2021 - Enabling rapid COVID-19 small molecule drug design through scalable deep learning of generative models
- April 1, 2021 - COVID-19 HPC Consortium reflects on past year
- February 19, 2021 - Physics of particle dispersion may lend insight into reducing the airborne spread of COVID-19 virus
- January 19, 2021 - LLNL and United Kingdom company to collaborate on development of universal coronavirus vaccine
- November 18, 2020 - Model for COVID-19 drug discovery a Gordon Bell finalist
- November 12, 2020 - LLNL welcomes 'Ruby' supercomputer for national nuclear security mission and COVID-19 research
- November 4, 2020 - Mammoth computing cluster to aid COVID research
- October 19, 2020 - AI gets a boost via LLNL, SambaNova collaboration
- October 7, 2020 - Corona supercomputer gets funding for COVID-19 work
- June 25, 2020 - Lab technologies help fight COVID-19
- June 9, 2020 - Lab, BMI produce FDA-approved emergency ventilator
- June 8, 2020 - Multi-lab research to improve COVID-19 diagnostics
- May 29, 2020 - Lab team studies calibrated AI and deep learning models to more reliably diagnose and treat disease
- May 21, 2020 - Lab provides assistance in national swab shortage
- May 19, 2020 - COVID-19 research goes public through new portal
- May 14, 2020 - Deactivating coronavirus on N95 respirators for reuse
- May 1, 2020 - LLNL’s new machine learning platform generates novel COVID-19 antibody sequences for experimental testing
- April 29, 2020 - LLNL develops ‘stopgap’ ventilator for COVID-19 use
- April 21, 2020 - Upgrades for LLNL supercomputer from AMD, Penguin Computing aid COVID-19 research
- March 26, 2020 - New partnership to unleash U.S. supercomputing resources in the fight against COVID-19
- March 26, 2020 - Lab antibody, anti-viral research aids COVID-19 response
- February 3, 2020 - Lawrence Livermore researchers release 3D protein structure predictions for the novel coronavirus
- April 21, 2021 - Corona vs coronavirus: AMD and Penguin Computing to upgrade aptly named LLNL supercomputer
- April 1, 2021 - Beating back the coronavirus requires a bigger arsenal
- March 26, 2021 - The COVID-19 HPC Consortium looks ahead to a ‘National Strategic Computing Reserve’
- March 22, 2021 - What is a universal coronavirus vaccine and is it achievable?
- February 21, 2021 - 'This has to be the moment' to invest in coronavirus vaccines and treatments against future pandemics, experts warn
- February 11, 2021 - Worries About Viral Resistance to Covid-19 Vaccines Are Overdone
- January 13, 2021 - Why There's Still Need for Rapid Accessible Pathogen Testing, During and After the Crisis
- November 4, 2020 - AMD-Supermicro-Cornelis (Omni-Path) ‘Mammoth’ cluster at LLNL targets COVID-19
- May 5, 2020 - Advanced manufacturing innovation helps industry in COVID-19 fight
- May 5, 2020 - 3-D printed COVID-19 test swabs pass their own tests
- May 4, 2020 - Swab Shortage: FATHOM & Abiogenix Bridge the Gap with 3D Printed NP Swabs
- April 14, 2020 - LLNL’s Jim Brase explains how DOE labs are fighting (and coping with) COVID-19
- February 5, 2020 - Coronavirus: Lawrence Livermore Lab researchers examine virus in hopes of blocking, treating it
For more information about the U.S. government's response to COVID-19, see coronavirus.gov and usa.gov/coronavirus. For the latest public health and safety information from the Centers for Disease Control and Prevention, see cdc.gov/coronavirus.